Botulinum toxin. Determination in foods, feeds and animal sample materials. (NMKL 79, 3. ed., 2012)
Botulinum neurotoxins are highly toxic to man, higher mammals and fish, acting by blocking the cholinergic synapses of the nervous system . The work with these toxins requires special security measures in the laboratory .
This is a biological method and the principles of ethical animal experimentation must be followed. Use of this method requires appropriate license from national authorities. Redundant animal experiments must not be done. Selection of sample dilutions and/or neutralizing antibodies to be tested must be carefully considered based on expertise to avoid redundant testing.
Botulinumtoksiini. Osoittaminen elintarvikkeista, verestä ja muista näytemateriaaleista. (NMKL 79, 2012)
The 2nd ed. is available the 3rd ed. is sent to translation.